"Impacto do tratamento empírico da citomegalovirose em pacientes não transplantados do sul do Brasil".

Abstract

The treatment for cytomegalovirus in hospitals has been performed using the intravenous ganciclovir drug based on the presence or absence of clinical signs, which can establish numerous problems for the patient as well as economic impact in the health area. Among the main disadvantages of treatment without a previous diagnosis can be mentioned the cost of the drug, classifying treatment for cytomegalovirus as a major public health challenge. The aim of this study was to analyze the impact of cytomegalovirus treatment in non-transplanted patients from southern Brazil. A retrospective cross-sectional study involving data from patients with a diagnostic hypothesis of cytomegalovirus who used the drug ganciclovir hospitalized from 2009 to 2017 at a Teaching Hospital located in the City of Santa Cruz do Sul, RS, Brazil, was conducted. The list of patients was obtained through the Hospital Internal Pharmacy System and the data were collected in medical records made available by the Medical and Statistical Archiving Service of the hospital, where a sociodemographic and managed dosage search was performed to calculate the cost of Ganciclovir. For hospitalization cost analysis, the files of the Hospital Inpatient Authorization were used. A total of 31 patients who used the drug ganciclovir were found, with 54.8% being children. 58.1% of the patients were attended by SUS. The children had longer hospitalization time compared to adults (p<0,05) and the cost of treatment was also higher. The cost of treatment increases especially due to the need to dispose of considerable volumes of medication, which impacted at an average cost of R $ 2,007.01 only for the disposal of bottles containing unused medication volumes. It is concluded that the group of children causes higher expenditures in the hospital, when it is analyzed the high cost originated by the use of ganciclovir, as well as high values that are spent with hospitalization and with wasted medication due to the absence of bottles containing smaller volumes for pediatric use.