http://hdl.handle.net/11624/182 2026-03-28T15:21:32Z http://hdl.handle.net/11624/4198 Title: Lesões periapicais de origem endodôntica em pacientes portadores de diabetes mellitus. Authors: Cole, Ricardo Abstract: The Diabete Mellitus (DM) is a metabolic disease that affects more than 800 millions of people in the world, with projections of reaching 1,3 billions cases until 2050. DM intensifies the inflammatory processes, bringing forward necrosis and its consequences in the pulp and periradicular tissues. The present study, through a literature review, aimed to investigate the influence of Diabetes Mellitus (DM) in periapical lesions of endodontic origin. The analysis of these studies demonstrated that diabetic patients have a reduced success rate in endodontic treatment due to difficulty in healing and a larger tendency to develop periapical lesions in previously treated teeth. These inherent systemic modifications to pathology interfere with the prevalence, symptomatology, and healing of these lesions. Several authors highlight that the better the glycemic control, the lower are the risks of adverse complications. However, chronic inflammation induced by periapical lesions and methodological limitations can interfere in the results. Furthermore, diabetic patients will present higher endodontic lesions prevalences, which compromises the monitoring and the endodontic success determination. It is concluded that, although DM interferes with periapical lesions, glycemic control will contribute to the endodontic treatment success. These studies reinforce the importance of individualizing treatment plans for these patients, which may include adjunctive therapies alongside conventional treatment. Although there is no cure, medication therapy and lifestyle changing are essential for good glycemic control, preventing major complications. 2025-01-01T00:00:00Z http://hdl.handle.net/11624/4197 Title: Uso e eficácia da pasta CTZ (Cloranfenicol, Tetraciclina e Óxido de Zinco e Eugenol) : revisão de literatura. Authors: Coelho, Lúcia da Silva Abstract: Considering the importance of keeping deciduous teeth in the mouth, to maintain space for the permanent successor tooth, among other aspects, it is If necessary, the dentist intervenes in different treatment needs, including exfoliation. Among these needs is endodontics, which traditionally recommends the instrumentation of root canals. However, there is also a technique that recommends not instrumenting the root canals and using pastes. The most used paste in these situations, in Latin America, including Brazil, is CTZ (antibiotic paste composed of chloramphenicol, tetracycline and zinc oxide). Thus, the objective of this work was to analyze the possibility of using CTZ paste in endodontics for primary teeth, especially in public health. To this end, a literature review was carried out, evaluating the indications, advantages and limitations of using the paste. Most of the articles found were case reports, with few articles evaluating the use of the paste through longitudinal clinical studies. The technique is indicated for deciduous teeth with pulp necrosis, where maintaining the tooth for longer contributes to the child's oral health. The success of the treatment is based on the correct diagnosis, through careful anamnesis, clinical and radiographic examinations, as well as the adequate execution of the technique and monitoring of patients, through clinical and radiographic examinations. One of the advantages of using CTZ paste is its ease of use, when compared to the conventional technique, as it recommends treatment in a single session, eliminating the need for root canal instrumentation. Most non-instrumental treatment failures are observed only in radiographic evaluation, making this exam essential for monitoring treated cases, which would be a limitation for its adoption in services that do not perform x-rays. The technique is contraindicated in patients at risk of infective endocarditis, pre- or post transplant patients, immunocompromised patients, or with a history of allergy to any of the medications used in the pastes. Furthermore, it should not be used on teeth that cannot be restored; or when root resorption involves more than half of one of the roots; teeth with extensive internal resorption, root calcification and perforation of the floor of the pulp chamber. It is concluded that the use of CTZ paste in the endodontic treatment of primary teeth is a more conservative option, easier to use, faster and with less need for available instruments, when compared to the conventional technique, which favors its use in healthcare. public. However, it requires an initial x-ray and clinical and radiographic follow-up, which is not always available in public services. Carrying out more follow-up research on CTZ paste would make it possible to increase the level of evidence of its use in primary dentition, favoring its use in public health. 2024-01-01T00:00:00Z http://hdl.handle.net/11624/4196 Title: Tratamento periodontal em pacientes de risco para osteorradionecrose. Authors: Pinheiro, Gabriel Benicio Sehgno Abstract: Osteoradionecrosis is a complication resulting from radiotherapy treatment used in head and neck cancer, which affects the periodontium, the set of oral structures responsible for supporting the teeth and protecting against pathogenic microorganisms. When these structures undergo an inflammatory process, periodontal disease is characterized, manifesting as clinical attachment loss, periodontal pocket formation, and gingival bleeding on probing, among other signs. These manifestations are aggravating risk factors for the development of ORN (osteoradionecrosis). Radiotherapy, which uses radiation to eliminate cancerous cells, constitutes an important risk factor for osteoradionecrosis, a condition that directly affects the periodontium, compromising the supporting structures, especially when exposed to high doses of radiation. Osteoradionecrosis is characterized by intense pain, dysphagia, malnutrition, and may present with fistulas, ulcers, devitalized bone exposure, bleeding, and delayed healing. Therapeutic intervention involves the use of less invasive procedures and, in severe cases, requires invasive procedures. This study aimed to present periodontal management interventions in patients with the potential to develop osteoradionecrosis, as well as to show the effects of radiotherapy on the periodontium and also the etiology and complications of osteoradionecrosis. The methodology consisted of a literature review conducted through searches in the PubMed, Portal de Periódicos da CAPES and SciELO databases, using articles published between 2015 and 2025. The results indicated that periodontal treatment in irradiated patients should prioritize preventive and minimally invasive approaches (biofilm control, use of fluoride and chlorhexidine solutions, systemic antimicrobials, and ultrasound) to stabilize oral health and mitigate the risk of ORN. It is concluded that invasive procedures, such as tooth extractions and bone resections, should be reserved as a last resort, after conservative therapies have failed, given the fragility of irradiated tissue. 2025-01-01T00:00:00Z http://hdl.handle.net/11624/4195 Title: Diamino fluoreto de prata como abordagem minimamente invasiva ao tratamento da cárie dentária na odontopediatria. Authors: Moura, Daniele Weis Fernandes de Abstract: This study aimed to investigate the main clinical indications of Silver Diamine Fluoride (SDF) in pediatric dentistry, presenting its effectiveness in controlling dental caries and how this approach is understood and accepted by parents or guardians, who are essential for adherence to child treatment. It is a literature review conducted through bibliographic searches in the PubMed, SciELO, and CAPES Journal Portal databases, using DeCS descriptors and including publications between 2020 and 2025, in Portuguese and English. The analyzed studies demonstrated that SDF is highly effective in arresting carious lesions in primary teeth due to its antimicrobial and remineralizing action resulting from the combination of silver and fluoride ions. This characteristic allows the control of disease progression in a simple, quick, and painless way, being especially indicated for children with multiple lesions, high caries risk, or cooperation difficulties, in addition to representing a viable alternative in contexts with limited resources. The results indicate consensus regarding the need for standardized clinical protocols to ensure biosafety and effectiveness, although divergences exist regarding the prior removal of carious dentin, prophylaxis before application, ideal product contact time, and frequency of reapplications. In general, biannual reapplications proved more effective in controlling the disease, although some studies recommend earlier evaluations to ensure therapeutic success. The 38% concentration was the most commonly used and associated with better clinical outcomes, providing greater mineral deposition and antibacterial effect. Among the limitations, the irreversible darkening of treated lesions stands out, which may affect aesthetic acceptance and requires informed consent and clear communication between professionals and caregivers. SDF does not completely replace restorative procedures but can be used as an intermediate step. It is concluded that Silver Diamine Fluoride stands out as a safe, effective, and accessible therapeutic agent in pediatric dentistry, promoting a preventive and humanized practice aligned with the principles of Minimally Invasive Dentistry and the promotion of children's oral health. 2025-01-01T00:00:00Z